ESM Ingredients

ESM Technologies, the leading supplier of innovative, commercialized eggshell and eggshell membrane wellness ingredients, is excited to announce the publication of a safety manuscript for their flagship ingredient NEM®.  The manuscript entitled “Safety evaluation of a natural eggshell membrane-derived product” has been published online ahead of print in the journal Food and Chemical Toxicology (http://dx.doi.org/10.1016/j.fct.2011.12.036). [...]

A new pre-clinical research study on NEM® (Natural Eggshell Membrane), published in the Journal of Medicinal Food, looks at NEM’s mechanism of action in order to gain insight into NEM’s clinical efficacy in reducing joint pain and stiffness. It has been published online ahead of print, (http://www.liebertonline.com/doi/pdfplus/10.1089/jmf.2011.0197).  Please look for the print edition of the [...]

The effects of chitin-glucan (CG) on early atherosclerosis, cardiac production of superoxide anion, and hepatic antioxidant enzymes were studied in an animal model of atherosclerosis. Three groups of 12 hamsters were fed an atherogenic diet for 12 weeks. They received by gavage either water (control group) or CG in water at a dose of 21.4 [...]

The effects of chitin-glucan on early atherosclerosis and cardiac production of superoxide anion and hepatic antioxidant enzymes were evaluated in a hamster model of nutritionally induced atherosclerosis, a model similar in many respects to human atheroma, with all signs of high oxidative stress. The study showed that regular consumption of chitin-glucan is efficient in preventing [...]

Recent studies have provided new evidence that alterations in the composition of the gut microbiota – known as dysbiosis – participate in the development of obesity. The aim of the present study was to investigate the ability of chitin-glucan (CG) from a fungal source to modulate both the gut microbiota and glucose and lipid metabolism [...]

Chitin-glucan is an insoluble biopolymer, composed of chitin and beta-(1,3)-D-glucan, that is a component of the fungal cell wall. This study was conducted to assess the safety of chitin-glucan from the mycelium of Aspergillus niger (Artinia brand) for use as dietary supplement and food ingredient. Chitin-glucan was fed to Wistar rats (20/sex/group) at dietary levels [...]

ESM Technologies’ NEM® (Natural Eggshell Membrane) is a proven ingredient for the joint health market that delivers fast results. Two 30-day open label human clinical trials were conducted to evaluate NEM (500mg once daily) as a treatment for various joint and connective tissue disorders.

  Introduction  Natural Eggshell Membrane (NEM®) is a new novel dietary supplement that contains naturally occurring glycosaminoglycans and proteins essential for maintaining healthy articular cartilage and the surrounding synovium.  The randomized, multicenter, double blind, placebo controlled Osteoarthritis Pain Treatment IncorpOrating NEM® (OPTION) clinical study was conducted to evaluate the efficacy and safety of NEM® as [...]

Eggshell Calcium (ESC®) is one of nature’s purest and most absorbable forms of calcium and has been clinically proven to increase bone density. ESC® naturally combines calcium carbonate with inherent transport proteins for maximum absorption and essential trace minerals for increasing bone mineral density. Heavy metals in dietary supplements have been highly regulated by the government [...]

In this paper the most significant biological and clinical aspects of a biopreparation made of chicken eggshells are reviewed. Eggshell powder is a natural source of calcium and other elements (e.g. strontium and fluorine) which may have a positive effect on bone metabolism. Experimental and clinical studies performed to date have shown a number of [...]

Chicken eggshell powder has been proposed as an attractive source of calcium for human health to increase bone mineral density in an elderly population with osteoporosis. However, factors affecting calcium transport of eggshell calcium have not yet been evaluated. Chicken eggshell contains about 1.0% (w/w) matrix proteins in addition to a major form of calcium [...]

Although bone metabolism is largely under genetic control, the role of nutrition is considerable. The present study evaluates the effects of chicken eggshell powder, a new source of dietary Ca, and purified CaCO3 on bone mineral density (BMD) of the lumbar spine and hip. Besides BMD we also looked at biochemical markers of bone and [...]

Based on the high calcium content, chicken egg shells are an interesting source of calcium. We studied the short-term effects on bone mineral density (BMD) of the lumbar spine and hip in 9 women and one man (mean age +/- SD, 63.9 +/- 8.1 years) with osteoporosis or osteopenia. Also the effects on pain and [...]